Living with long-term pain or ME/CFS can affect every part of life, including mood, sleep, confidence and stress levels. When mental health suffers, pain and fatigue often become harder to manage. NHS Talking Therapies is a free and confidential service that can help you develop practical tools to cope better, improve wellbeing and regain control. Support is available for problems such as stress, anxiety, low mood and overwhelm, all of which can have a real impact on persistent pain and fatigue symptoms.